Dutch symposium – Light and the ageing brain.
Dutch Symposium – Light and the ageing brain.
Van de Werken M., Booij S.H., van der Zwan J.E., Simons M.J.P, Gordijn M.C.M, & Beersma D.G.M. The biological clock modulates the human cortisol response in a multiplicative fashion. Chronobiology International, 31:572-580. (2013)
Human cortisol levels follow a clear circadian rhythm. We investigated the contribution of alternation of sleep and wakefulness and the circadian clock, using forced desynchrony. Cortisol levels were best described by a multiplication of a circadian and a wake-time component. The human cortisol response is modulated by circadian phase. Exposure to stress at an unnatural phase, as in…
Doctoral thesis. Maan van de Werken. Dawn, Light at night and the clock: impact on human alertness, performance and physiology. University of Groningen, The Netherlands. 2013.